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KMID : 0861020070220010035
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Korea Journal of Herbology
2007 Volume.22 No. 1 p.35 ~ p.40
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A Study on the Therapeutic Effect of Alzheimer’s Disease of Ginseng Radix plus Crataegi Fructus
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Han Sin-Hee
Kil Ki-Jung
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Abstract
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Objectives : This in vitro research was conducted to investigate the effect of the Ginseng Radix plus Crataegi Fructus. on the cytokine protein release and Nitric oxide release in releted to Alzheimer’s disease.
Methods : Specifically, the effects of the Ginseng Radix plus Crataegi Fructus extract on $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ of BV2 microglia cell line treated with lipopolysacchride.
Results: The Ginseng Radix plus Crataegi Fructus extract suppressed the production of inflammatory cytokine protein $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ and in BV2 microglia cell line treated with lipopolysacchride.
Conclusion: These results suggest that the Ginseng Radix plus Crataegi Fructus extract may be effective for the prevention and treatment of Alzheimer’s disease. Investigation into the clinical use of the Gin-CHF extract for Alzheimer’s disease is suggested for future research.
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KEYWORD
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Ginseng Radix, Crataegi Fructus, Alzheimer’s disease
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